S a f e t y D a t a S h e e t

According to Regulation (EC) 1907/2006

Identification of the substance/preparation and of the company or firm

1.1 Identification of the substance or preparation

Name:

Benzidine

1.2 Synonym:

4,4#-Diaminobiphenyl

1.3 Use of the substance/preparation:

For laboratory utilisation, analysis, research and fine chemistry.

1.4 Identification of the company or firm:

PANREAC QUIMICA S.L.U.

C/Garraf 2

Polígono Pla de la Bruguera

E-08211 Castellar del Vallès

(Barcelona) Spain

Tel. (+34) 937 489 400

e-mail: product.safety@panreac.com

Emergencies:

Single telephone number for emergency calls: 112 (EU)

Tel.: (+34) 937 489 499

Identification of dangers

Classification of the substance or the mixture.

Classification Regulation (CE) nº 1272/2008.

Carc. 1A

Acute Tox. 4

Aquatic Acute 1

Aquatic Chronic 1

Hazard Pictograms

Signal word

Danger

Hazard statements

H350 May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.

H302 Harmful if swallowed.

H410 Very toxic to aquatic life with long lasting effects.

Precautionary statements

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.

P264 Wash...thoroughly after handling.

P270 Do no eat, drink or smoke when using this product.

P273 Avoid release to the environment.

P281 Use personal protective equipment as required.

Classification (67/548/CEE or 1999/45/CE).

For the full text of the R-phrases mentioned in this section, see section 16.

Component Composition/Information

Name: Benzidine

Formula: (C6H4NH2)2 M.= 184,24 CAS [92-87-5]

EC number (EINECS): 202-199-1

EC index number: 612-042-00-2

First aid

4.1 General indications:

Never provide drink or induce vomiting in the event of loss of consciousness.

4.2 Inhaling:

Take the person out into the fresh air. In the event of suffocation, proceed to provide artificial respiration.

4.3 Contact with the skin:

Wash with plenty of water. Remove contaminated clothing.

4.4 Eyes:

Wash with plenty of water, keeping eyelids open.

4.5 Swallowing:

Drink large amounts of water. Induce vomiting. Seek medical assistance.

Fire-fighting means

5.1 Suitable fire-extinguishing means:

Carbon dioxide (CO2). Dry powder. Foam.

5.2 Fire-fighting means which must NOT be used:

5.3 Special risks:

Combustible. In the event of fire, fumes may form:

5.4 Protective equipment:

Measures to be taken in the event of accidental spillage

6.1 Individual precautions:

Do not inhale the dust. Avoid contact with the skin, eyes or clothing.

6.2 Precautions for care of the environment:

Do not allow it to enter the drainage system. Avoid pollution of the soil, water supplies and drains.

6.3 Methods for collection/cleaning:

Collect up dry and deposit in waste containers for subsequent elimination in accordance with current legislation.

Handling and storage

7.1 Handling:

No special indications.

7.2 Storage:

Well sealed containers.Dry atmosphere.Atmospheric temperature.

Staff exposure/protection controls

8.1 Technical protective measures:

8.2 Exposure limit control:

:

8.3 Respiratory protection:

Use suitable breathing equipment. Filter A. Filter P3.

8.4 Hand protection:

Use suitable gloves

8.5 Eye protection:

Use suitable goggles.

8.6 Individual hygiene measures:

Remove contaminated clothing. Wash hands before breaks and when the job is done.

8.7 Environmental exposure controls:

Fulfill the commitments under local environmental protection legislation.

Physical and chemical properties

Appearance: solid

Colour:

Granulometry:

Odour:

pH:

Melting point/freezing point: 128 °C

Initial boiling point and boiling range: ~400 °C

Flash point:

Flammability (solid, gas):

Upper/lower flammability or explosive limits:

Vapour pressure:

Vapour density:

Relative density:

Solubility: 0,4 g/l water 20 °C

Partition coefficient: n-octanol/water:

Auto-ignition temperature:

Decomposition temperature:

Viscosity:

Stability and reactivity

10.1 Conditions which should be avoided:

10.2 Matter which should be avoided:

10.3 Hazardous decomposition products:

NOx, CO, CO2.

10.4 Complementary information:

Toxicological information

• Acute toxicity:

LD L0 oral rbt : 200 mg/kg

LD50 oral mus : 214 mg/kg

LD50 oral rat : 309 mg/kg

TC L0 inh man : 176 m

LD50 ipr mus : 110 mg/kg

• Dangerous effects for health:

If swallowed: Harmful to the health. Carcinogenic. Pregnant women must not be allowed to come into contact with the product. Possible risk of adverse effects to the foetus during pregnacy. Other dangerous characteristics are not discarded. Take the usual precautions for handling chemical products.

Environmental information

12.1 Mobility:

12.2 Ecotoxicity:

12.1.1 - EC50 test (mg/l):

Bacteria (Photobacterium phosphoreum) 50,7 mg/l

Classification:

Extr. toxic

12.2.2 - Receptor medium:

Risk for the water environment

High

Risk for the land environment

High

12.2.3 - Observations:

Extremely toxic in water supplies and soils. Ecotoxicity acute and chronic.

12.3 Degradability:

12.3.1 - Test:

12.3.2 - Biotic degradation classification:

BOD5/COD

Biodegradability

12.3.3 - Abiotic degradation depending on pH:

12.3.4 - Observations:

Data not available.

12.4 Accumulation:

12.4.1 - Test:

12.4.2 - Bioaccumulation:

Risk

12.4.3 - Observations:

Data not available.

12.5 Other possible effects on the environment:

Do not allow it to enter soils or water channels.

Water-pollutant product.

Considerations regarding elimination

13.1 Substance or preparation:

In the European Union, there are no homogeneous standards established for elimination of chemical waste, which is waste of a special nature, and treatment and elimination of same is subject to the domestic legislation in each country.

In view of this, in each case, you should contact the competent authority or those companies legally authorized for elimination of waste.

2001/573/EC: Council Decision of 23 July 2001 amending Commission Decision 2000/532/EC as regards the list of wastes.Council Directive 91/156/EEC of 18 March 1991 amending Directive 75/442/EEC on waste.

.

13.2 Contaminated containers:

Contaminated containers and packaging of dangerous substances or preparations must be treated in the same manner as the actual products contained in them.

European Parliament and Council Directive 94/62/EC of 20 December 1994 on packaging and packaging waste.

.

Information concerning transport

Overland (ADR):

Technical name: BENZIDINE

UN 1885 Class: 6.1 PELIG.M.AMB Packaging group: II (D/E)

By sea (IMDG):

Technical name: BENZIDINE

UN 1885 Class: 6.1 PELIG.M.AMB Packaging group: II

By air (ICAI-IATA):

Technical name: Benzidine

UN 1885 Class: 6.1 PELIG.M.AMB Packaging group: II

Packaging instructions: CAO 615 PAX 613

Regulatory information

The substance is subject to Regulation (EC) No 689/2008 of the European Parliament and of the Council of 17 June 2008 concerning the export and import of dangerous chemicals.

Other information

Other precautionary statements

P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

P308+P313 IF exposed or concerned: Get medical advice/attention.

P330 Rinse mouth.

P391 Collect spillage.

P405 Store locked up.

P501 Dispose of contents/container according to Directive 94/62/CE or 2008/98/CE.

Labelling (65/548/CEE or 1999/45/CE)

Review number and date: 3 3.11.10

Date published: 3.11.10

In respect of the previous review, changes have been made to the following sections: 2, 3, 15

The information included in this Safety Data Sheet is based on our most up-to-date knowledge, and is solely intended to inform regarding aspects of safety; the properties and characteristics indicated herein are not guaranteed.